Ipf scrnaseq atlas

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August undefined, 2024

Web ScRNA-seq analysis of IPF, SSc-ILD, and control myeloid populations. (A) UMAP plot of macrophage and dendritic cell populations, identified by cell type. (B) UMAP plot of macrophage and... Web18 nov. 2024 · This comprehensive molecular atlas identifies the biochemical functions of lung cells and the transcription factors and markers for making and monitoring them; defines the cell targets of...

Single-cell RNA-seq reveals ectopic and aberrant lung …

Web16 nov. 2024 · The IPF Cell Atlas Neumark et al have come up with a fascinating idea to help researchers and physicians conduct future studies on the IPF ECM: the creation of their IPF Cell Atlas . They noted that recent developments in single-cell RNA sequencing … WebIn this issue of the Journal, Deprez and colleagues (pp. 1636–1645) provide an scRNAseq atlas of the healthy human airway by profiling 77,969 cells from 10 subjects ( 3 ). By diligently sampling multiple locations along the respiratory tract, from the nasal epithelium to the distal tracheobronchial tree, they survey the cellular diversity of ... little creek oyster greenport

GEO Accession viewer - National Center for Biotechnology …

Web8 mei 2024 · With this in mind, we have created SchistoCyte Atlas i that presently includes the scRNAseq atlas made from over 40 000 cells from adult male and both sexually mature and immature female parasites [12. Wendt G. et al. A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding. Web21 apr. 2024 · Sequencing data processing for the large data set. scRNA-seq data of IPF and normal human lungs from the IPF Cell Atlas preprint 23. Sequencing data processing for publicly available data sets ... Web14 sep. 2024 · In order to improve our understanding of cell-specific mechanisms contributing to COPD pathogenesis, we analysed single-cell RNA sequencing (scRNAseq) profiles of explanted parenchymal lung tissue from 17 subjects with advanced COPD requiring transplant and 15 control donor lungs. little creek private dog park

The Idiopathic Pulmonary Fibrosis Cell Atlas American Journal of

A spatial multi-omics atlas of the human lung reveals a novel ... - bioRxiv

Web7 apr. 2024 · Macrophages are critical effector cells in both fibrosis progression and resolution (7, 10).Recent data have revealed “scar-associated macrophages” (SAMs) expressing TREM2 and/or CD9 in hepatic and pulmonary fibrosis (11–21).CD9 + TREM2 … WebIPF Cell Atlas : The Idiopathic Pulmonary Fibrosis (IPF) Cell Atlas (www.ipfcellatlas.com) is a multi-institutional collaboration that seeks to facilitate the exploration of several single-cell RNA sequencing datasets related to IPF in the form of an easy-to-use webtool. little creek new yorkWeb18 dec. 2024 · Generated scRNAseq atlas of E12, E14, E16, P1, P30, and adult SMG • Smgc and Bpifa2 define two proacinar populations in the developing SMG. Loss of Ybx1, Eno1, Sox11, and Atf4 associated with acinar phenotype. Gstt1 defines Kit-negative and sexually dimorphic intercalated duct cells little creek plantation gray ga

"http://www.ipfcellatlas.com/ " - Ipf scrnaseq atlas

Ipf scrnaseq atlas

GSEA analysis of the scRNAseq dataset against the GSEA …

WebThe scRNAseq analysis was based on publicly available genome-wide expression data and comprises all protein-coding genes in 536 individual cell type clusters corresponding to 15 different cell type groups. A specificity classification was performed to determine the number of genes elevated in these single cell types. WebGuo-Cheng Yuan, Long Cai, Michael Elowitz, Tariq Enver, Guoping Fan, Guoji Guo, Rafael Irizarry, Peter Kharchenko, Junhyong Kim, Stuart Orkin, John Quackenbush, Assieh Saadatpour, Timm Schroeder, Ramesh Shivdasani & Itay Tirosh. Genome Biology volume 18, Article number: 84 (2024) Single-Cell RNA Sequencing in Cancer: Lessons Learned …

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Web7 dec. 2024 · 19年发表在Nature Communications（12.12）的一篇文章An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics素。该研究使用转录组学（scRNA-seq和bulk RNA-seq）和基于蛋白质组学的质谱分析（mass spectrometry … WebscRNAseq to Understand Effects of Drug Treatment for IPF To date, Nintedanib and Pirfenidone are the only approved drugs for treatment of IPF ( 47, 48 ). Two recent studies employed scRNAseq to investigate the effects of drug treatment on cells from IPF patients.

WebWe provide a single cell atlas of Idiopathic Pulmonary Fibrosis (IPF), a fatal interstitial lung disease, ... demonstrates a new framework for analyzing complex disease with scRNAseq, ... Web14 okt. 2024 · A new molecular atlas of the disease, produced by scientists at Memorial Sloan Kettering, sheds light on what makes the cancer so aggressive. Within SCLC tumors, a rare population of stem cell-like cells have molecular characteristics that make them more likely to spread, or metastasize.

Web27 mei 2024 · Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown etiology and with limited therapeutic options. Over the years, progress in IPF research has been hindered by a lack... Web8 jul. 2024 · ScRNAseq highlights genomic heterogeneity in glioblastoma We used droplet-based scRNAseq 32, 33, 34 to obtain the transcriptome of cells isolated from freshly excised IDHwt glioblastoma and...

Web30 nov. 2024 · Their scRNAseq study, which analyzed the transcriptomes of 24,220 cells from the upper and lower lobes of seven control and three IPF samples, identified three distinct pulmonary macrophage subsets in the IPF lung: FABP4 hi macrophages, SPP1 …

Web20. comparative analysis of 2 scRNAseq studies on IPF 21. Earlier scRNAseq studies on IPF • FACS sort for CD45-CD31-CD326+ HTII-280+ AT2 cells • 3 IPF (325 cells) + 3 Ct lungs (215 cells) • IPF AT2 cells coexpress AT1, AT2 and conducting airway selective … little creek north carolinaWebThe COVID Cell Atlas (www.covidcellatlas.com) is a publicly available and interactive webtool designed to facilitate the independent exploration of single-cell RNA sequencing data generated from the peripheral blood mononuclear cells of patients diagnosed with … little creek overlook blue ridge gaWeb8 dec. 2016 · Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease characterized by airway remodeling, inflammation, alveolar destruction, and fibrosis. We utilized single-cell RNA sequencing (scRNA-seq) to identify epithelial cell types and … little creek neighborhood centerWeb9 mei 2024 · Dysregulation of intestinal ILC function has been associated with both the pathogenesis of IBD and colitis-associated cancer. 74–77 Different ILC subsets are enriched in specific intestinal locations, with ILC1 enriched in the upper gastrointestinal tract, ILC2 present throughout the entire intestine, and ILC3 mostly enriched in the colon. 78 … little creek photography in wallace ncWeb1 jul. 2024 · More recently, the promise of this approach has expanded exponentially with the implementation of single-cell RNA sequencing (scRNAseq) approaches. Studies have used scRNAseq to characterize cells from the parasite’s intramolluscan stage [ 9 ], larval [ 10 ] and juvenile [ 11 ] intramammalian forms, and adult male and female parasites [ 12 ]. little creek residential arkansasWeb9 sep. 2024 · We provide a single cell atlas of Idiopathic Pulmonary Fibrosis (IPF), a fatal interstitial lung disease, focusing on resident lung cell populations. By profiling 312,928 cells from 32 IPF, 29 healthy control and 18 chronic obstructive pulmonary disease (COPD) … little creek psd appointmentWebThis pipeline performs basic analysis of sc RNA-Seq data generated using the 10X genomics protocol. It produces cell x gene count matrices using the Cell Ranger software. In addition matrices for RNA velocity analysis are created using velocyto and ready to use … little creek park winston salem nc