Sialate o-acetylesterase-like

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August undefined, 2024

WebMentioning: 15 - The "nonspecific" esterases are a family of enzymes that were originally identified because of their reaction with synthetic 0-acetyl ester substrates. While the … Websialate-O-acetylesterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid release by NanH, its cognate sialidase. Biochemical Journal, 472 (2). 157 - 167.

Sialate O-acetylesterase Wiki

WebAug 18, 2024 · In this perspective, the balance between synthesis and degradation of O-acetylated NeuAc, performed by sialic acid O-acetyltransferase, SOAT (encoded by the CASD1 gene) and sialate O-acetylesterase (SIAE), respectively, represents an important regulation point in the complex network of NeuAc biological functions (Mandal et al. 2015). The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate In human it is encoded by the SIAE gene located on chromosome 11. This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. … See more SIAE activity negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance. It down-regulates B lymphocyte antigen receptor signaling (involving See more The SIAE gene contains 15 exons and expresses a protein that is approximately 56 kDa in size. It is known to be expressed in the adult See more Genetic defects in SIAE have been associated with multiple autoimmune diseases. Loss of function mutations in SIAE are much more frequently found in humans with See more northfield just foods

Recombinant viral sialate-O-acetylesterases - Semantic Scholar

WebJan 26, 2012 · Like influenza C virus HEF, most nidovirus HEs bind to 9-O-acetylated (9-O-Ac) Sias and, correspondingly, display sialate-9-O-acetylesterase receptor-destroying enzyme activity . Murine coronaviruses, however, occur in two closely related biotypes that differ in HE ligand/substrate preference. WebNov 10, 2024 · Sialate O acetylesterase. Updated on Nov 10, 2024. Edit. Like. Comment. EC number 3.1.1.53 IntEnz IntEnz view ExPASy NiceZyme view: CAS number 89400-31-7 … how to say 12 in asl

Specific Synthesis of Neurostatin and Gangliosides O- Acetylated …

SIAE Gene - GeneCards SIAE Protein SIAE Antibody

WebJun 13, 2024 · Mandal, C., Chandra, S. & Schauer, R. Regulation of O-acetylation of sialic acids by sialate-O-acetyltransferase and sialate-O-acetylesterase activities in childhood … Websialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the … northfield junior school twitterWebJul 14, 2015 · First, we analysed whether sCASD1 possesses esterase activity, since the GDSL/SGNH fold is usually found among hydrolytic enzymes 38, including the sialate 9-O … how to say 12 45 in spanish

"WebSialate-O-acetylesterase was purified almost 900-fold from particle-free supernatants of horse liver by gel filtration, ion-exchange chromatography and isoelectric focussing. The … " - Sialate o-acetylesterase-like

Sialate o-acetylesterase-like

CDD Conserved Protein Domain Family: sialate_O-acetylesterase_li…

WebProtein: PTPRK Receptor-type tyrosine-protein phosphatase kappa, Protein-tyrosine phosphatase kappa, R-PTP-kappa, EC 3.1.3.48 Gene: PTPRK Organism: Homo sapiens WebJan 4, 2024 · called lambda-like because they carry several genes homologous with bacteriophage lambda. Proceedings 2024, 66, ... environments, such as mucus [13–15]. Our study showed that NanS-p sialate O-acetylesterase was carried by all studied Stx2a phages, suggesting an important role for Stx2a phage biology or for its bacterial host.

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WebThe cloned and expressed several recombinant viral O-acetylesterases and esterase knockout proteins of the influenza C virus hemagglutinin-esterase, which can be used to unambiguously identify O-acetylated acids in a variety of assays. Viral O-acetylesterases were first identified in several viruses, including influenza C viruses and coronaviruses. … WebMar 30, 2024 · The O-glycan structures ... Kriaris M. S., Hoskins L. C. (1992). Mucin degradation in the human colon: production of sialidase, sialate O-acetylesterase, N …

Web3.1.1 Carboxylic-ester hydrolases. 3.1.1.53 sialate O-acetylesterase. IUBMB Comments. Acts on free and glycosidically bound N-acetyl- or N-glycoloyl-neuraminic acid; acts mainly on the 4-O- and 9-O-acetyl groups. Also acts on some other O-acetyl esters, both cyclic and acyclic compounds, which are not sialic acids. Specify your search results. WebJan 4, 2024 · called lambda-like because they carry several genes homologous with bacteriophage lambda. Proceedings 2024, 66, ... environments, such as mucus [13–15]. …

WebSialate O-acetylesterases are enzymes that change sialic acids that are free or bound to sidechains on proteins. They catalyze the removal of O-acetyl ester groups from position … WebFind sialate o-acetylesterase and related products for scientific research at MilliporeSigma. US EN. Applications Products Services Support. Advanced Search. Structure Search. Search Within. Products Technical Documents Site Content Papers Genes Chromatograms. Available for Sale. United States Globally.

WebMar 21, 2024 · enables sialate O-acetylesterase activity: IDA, IBA: 23308225: GO:0016787 5: hydrolase activity: IEA: GO:0106330 3 5: enables sialate 9-O-acetylesterase activity: IEA: …

WebJan 1, 2015 · Targetting 9-O-acetylated GD3 with sialate-9-O-acetylesterase results in apoptosis of biopsy-derived human glioblastoma cells. Compared to treatment of cells with exogenous O -acetylesterase, the effect of de- O -acetylation is more pronounced when the esterase is expressed within the cells from a recombinant baculovirus vector [ 127 ]. northfield kid venturesWebSpecific Synthesis of Neurostatin and Gangliosides O-Acetylated in the Outer Sialic Acids Using a Sialate Transferase Lorenzo Romero-Ramı´rez1,2*, Isabel Garcı ´a-Alvarez1,3, Ramo´n Campos-Olivas4, Michel Gilbert5, Marie- France Goneau5, Alfonso Ferna´ndez-Mayoralas3, Manuel Nieto-Sampedro1,2 1Unidad de Neurologı´a Experimental, Hospital … how to say 12 50 in spanishWebcytosolic sialic acid 9-O-acetylesterase homolog; sialate O-acetylesterase; sialic acid-specific 9-O-acetylesterase; sialate O-acetylesterase-like; clone 165; yolk sac gene 2; yolk sac protein 2; H-Lse; sialic acid-specific acetylesterase II; … northfield kentuckyWebNov 13, 2015 · Characterization of a Sialate-O-Acetylesterase (NanS) From the Oral Pathogen Tannerella Forsythia That Enhances Sialic Acid Release by NanH, Its Cognate Sialidase ... Cloning, Expression and Purification of Trypsin-Like Protease of the Periodontal Pathogen Tannerella Forsythia ATCC 43037 ZANCO JOURNAL OF PURE AND APPLIED … how to say 12 am in japaneseWebMar 1, 2001 · Description. Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, … how to say 12 in koreanWebJul 1, 2008 · The scissors represent the sialate-9-O-acetylesterase and sialate-4-O-acetylesterase involved in hydrolysis of the ester groups: The O-acetyl group at the Sia … how to say 12 in roman numeralsWeb3.1.1 Carboxylic-ester hydrolases. 3.1.1.53 sialate O-acetylesterase. IUBMB Comments. Acts on free and glycosidically bound N-acetyl- or N-glycoloyl-neuraminic acid; acts mainly … how to say 12 in sign language